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Poly(ADP-ribose) mediates the BRCA2-dependent early DNA damage response

Breast Cancer Susceptibility Gene 2 (BRCA2) plays a key role in DNA damage repair for maintaining genomic stability. Previous studies have shown that BRCA2 contains three tandem oligonucleotide/oligosaccharide binding folds (OB-folds) that are involved in DNA-binding during DNA double-strand break r...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Zhang, Feng, Shi, Jiazhong, Bian, Chunjing, Yu, Xiaochun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794993/
https://ncbi.nlm.nih.gov/pubmed/26489468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.040
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