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Poly(ADP-ribose) mediates the BRCA2-dependent early DNA damage response
Breast Cancer Susceptibility Gene 2 (BRCA2) plays a key role in DNA damage repair for maintaining genomic stability. Previous studies have shown that BRCA2 contains three tandem oligonucleotide/oligosaccharide binding folds (OB-folds) that are involved in DNA-binding during DNA double-strand break r...
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| Pubblicato in: | Cell Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794993/ https://ncbi.nlm.nih.gov/pubmed/26489468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.040 |
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