mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

The branched‐chain α‐ketoacid dehydrogenase (BCKDH) complex regulates branched‐chain amino acid (BCAA) catabolism by controlling the second step of this catabolic pathway. In the present study, we examined the in vivo effects of treatment with an mTORC1 inhibitor, rapamycin, on cardiac BCKDH complex...

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Bibliografiska uppgifter
I publikationen:FEBS Open Bio
Huvudupphovsmän: Zhen, Hongmin, Kitaura, Yasuyuki, Kadota, Yoshihiro, Ishikawa, Takuya, Kondo, Yusuke, Xu, Minjun, Morishita, Yukako, Ota, Miki, Ito, Tomokazu, Shimomura, Yoshiharu
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794793/
https://ncbi.nlm.nih.gov/pubmed/27047741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12007
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