Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia

Nonalcoholic fatty liver disease (NAFLD) is an increasing health problem worldwide, with genetic, epigenetic, and environmental components. Here, we describe the first example of NAFLD caused by genetic disruption of a mammalian potassium channel subunit. Mice with germline deletion of the KCNE2 pot...

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Vydáno v:Sci Rep
Hlavní autoři: Lee, Soo Min, Nguyen, Dara, Anand, Marie, Kant, Ritu, Köhncke, Clemens, Lisewski, Ulrike, Roepke, Torsten K., Hu, Zhaoyang, Abbott, Geoffrey W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794722/
https://ncbi.nlm.nih.gov/pubmed/26984260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23118
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