Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia

Nonalcoholic fatty liver disease (NAFLD) is an increasing health problem worldwide, with genetic, epigenetic, and environmental components. Here, we describe the first example of NAFLD caused by genetic disruption of a mammalian potassium channel subunit. Mice with germline deletion of the KCNE2 pot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Soo Min, Nguyen, Dara, Anand, Marie, Kant, Ritu, Köhncke, Clemens, Lisewski, Ulrike, Roepke, Torsten K., Hu, Zhaoyang, Abbott, Geoffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794722/
https://ncbi.nlm.nih.gov/pubmed/26984260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23118
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