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Mutations in a Highly Conserved Motif of nsp1β Protein Attenuate the Innate Immune Suppression Function of Porcine Reproductive and Respiratory Syndrome Virus

Porcine reproductive and respiratory syndrome virus (PRRSV) nonstructural protein 1β (nsp1β) is a multifunctional viral protein, which is involved in suppressing the host innate immune response and activating a unique −2/−1 programmed ribosomal frameshifting (PRF) signal for the expression of frames...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Yanhua, Shyu, Duan-Liang, Shang, Pengcheng, Bai, Jianfa, Ouyang, Kang, Dhakal, Santosh, Hiremath, Jagadish, Binjawadagi, Basavaraj, Renukaradhya, Gourapura J., Fang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794661/
https://ncbi.nlm.nih.gov/pubmed/26792733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03069-15
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