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Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers

Immobilization of nucleic acid aptamer recognition elements selected free in solution onto the surface of biosensor platforms has proven challenging. This study investigated the binding of multiple aptamer/target pairs immobilized on a commercially available microarray as a model system mimicking bi...

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Detalhes bibliográficos
Publicado no:J Nucleic Acids
Main Authors: Martin, Jennifer A., Chushak, Yaroslav, Chávez, Jorge L., Hagen, Joshua A., Kelley-Loughnane, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794571/
https://ncbi.nlm.nih.gov/pubmed/27042344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9718612
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