Protection against ventricular fibrillation via cholinergic receptor stimulation and the generation of nitric oxide

KEY POINTS: Animal studies suggest an anti‐fibrillatory action of the vagus nerve on the ventricle, although the exact mechanism is controversial. Using a Langendorff perfused rat heart, we show that the acetylcholine analogue carbamylcholine raises ventricular fibrillation threshold (VFT) and flatt...

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Pubblicato in:J Physiol
Autori principali: Kalla, Manish, Chotalia, Minesh, Coughlan, Charles, Hao, Guoliang, Crabtree, Mark J., Tomek, Jakub, Bub, Gil, Paterson, David J., Herring, Neil
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Special section reviews: Cardiac autonomic control in health and disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794549/
https://ncbi.nlm.nih.gov/pubmed/26752781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271588
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