Social stress-enhanced severity of Citrobacter rodentium induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri

Psychological stressors are known to affect colonic diseases but the mechanisms by which this occurs, and whether probiotics can prevent stressor effects, are not understood. Because inflammatory monocytes that traffic into the colon can exacerbate colitis, we tested whether CCL2, a chemokine involv...

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Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Mackos, Amy R., Galley, Jeffrey D., Eubank, Timothy D., Easterling, Robert S., Parry, Nicola M., Fox, James G., Lyte, Mark, Bailey, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794400/
https://ncbi.nlm.nih.gov/pubmed/26422754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.81
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