High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in Comparison to Simvastatin in UK GPRD Cohort

BACKGROUND & AIMS: Occasional risk of serious liver dysfunction and autoimmune hepatitis during atorvastatin therapy has been reported. We compared the risk of hepatotoxicity in atorvastatin relative to simvastatin treatment. METHODS: The UK GPRD identified patients with a first prescription for...

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Bibliographic Details
Published in:PLoS One
Main Authors: Clarke, Alan T., Johnson, Paul C. D., Hall, Gillian C., Ford, Ian, Mills, Peter R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794178/
https://ncbi.nlm.nih.gov/pubmed/26983033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151587
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