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Estradiol and Estrogen Receptor Agonists Oppose Oncogenic Actions of Leptin in HepG2 Cells

Obesity is a significant risk factor for certain cancers, including hepatocellular carcinoma (HCC). Leptin, a hormone secreted by white adipose tissue, precipitates HCC development. Epidemiology data show that men have a much higher incidence of HCC than women, suggesting that estrogens and its rece...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shen, Minqian, Shi, Haifei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794158/
https://ncbi.nlm.nih.gov/pubmed/26982332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151455
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