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Elucidating the genotype–phenotype map by automatic enumeration and analysis of the phenotypic repertoire

BACKGROUND: The gap between genotype and phenotype is filled by complex biochemical systems most of which are poorly understood. Because these systems are complex, it is widely appreciated that quantitative understanding can only be achieved with the aid of mathematical models. However, formulating...

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Détails bibliographiques
Publié dans:NPJ Syst Biol Appl
Auteurs principaux: Lomnitz, Jason G, Savageau, Michael A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794114/
https://ncbi.nlm.nih.gov/pubmed/26998346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjsba.2015.3
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