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2, 2′- and 4, 4′-Cyanines are Transporter Independent in vitro Dopaminergic Toxins with the Specificity and Mechanism of Toxicity similar to MPP(+)

Specific uptake through dopamine transporter (DAT) followed by the inhibition of the mitochondrial complex-I have been accepted as the cause of the specific dopaminergic toxicity of MPP(+). However, MPP(+) is taken up into many cell types through other transporters suggesting that in addition to the...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Kadigamuwa, Chamila C., Le Viet, Q., Wimalasena, Kandatege
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793973/
https://ncbi.nlm.nih.gov/pubmed/26094622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13201
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