Exosomal miR-10a derived from amniotic fluid stem cells preserves ovarian follicles after chemotherapy

Chemotherapy (CTx)-induced premature ovarian failure (POF) in woman remains clinically irreversible. Amniotic fluid stem cells (AFSCs) have shown the potential to treat CTx-induced POF; however, the underlying mechanism is unclear. Here we demonstrate that AFSC-derived exosomes recapitulate the anti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiao, Guan-Yu, Cheng, Chun-Chun, Chiang, Yih-Shien, Cheng, Winston Teng-Kuei, Liu, I-Hsuan, Wu, Shinn-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793229/
https://ncbi.nlm.nih.gov/pubmed/26979400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23120
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