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In-depth analysis of cis-determinants that either promote or inhibit reinitiation on GCN4 mRNA after translation of its four short uORFs

Translational control in eukaryotes is exerted by many means, one of which involves a ribosome translating multiple cistrons per mRNA as in bacteria. It is called reinitiation (REI) and occurs on mRNAs where the main ORF is preceded by a short upstream uORF(s). Some uORFs support efficient REI on do...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:RNA
Main Authors: Gunišová, Stanislava, Beznosková, Petra, Mohammad, Mahabub Pasha, Vlčková, Vladislava, Valášek, Leoš Shivaya
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793210/
https://ncbi.nlm.nih.gov/pubmed/26822200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055046.115
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