Structural Insight into Polymorphic ABO Glycan Binding by Helicobacter pylori

The Helicobacter pylori adhesin BabA binds mucosal ABO/Le(b) blood group (bg) carbohydrates. BabA facilitates bacterial attachment to gastric surfaces, increasing strain virulence and forming a recognized risk factor for peptic ulcers and gastric cancer. High sequence variation causes BabA functiona...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Moonens, Kristof, Gideonsson, Pär, Subedi, Suresh, Bugaytsova, Jeanna, Romaõ, Ema, Mendez, Melissa, Nordén, Jenny, Fallah, Mahsa, Rakhimova, Lena, Shevtsova, Anna, Lahmann, Martina, Castaldo, Gaetano, Brännström, Kristoffer, Coppens, Fanny, Lo, Alvin W., Ny, Tor, Solnick, Jay V., Vandenbussche, Guy, Oscarson, Stefan, Hammarström, Lennart, Arnqvist, Anna, Berg, Douglas E., Muyldermans, Serge, Borén, Thomas, Remaut, Han
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793151/
https://ncbi.nlm.nih.gov/pubmed/26764597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.12.004
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