Imaging Agonist-Induced D2/D3 Receptor Desensitization and Internalization In Vivo with PET/fMRI

This study investigated the dynamics of dopamine receptor desensitization and internalization, thereby proposing a new technique for non-invasive, in vivo measurements of receptor adaptations. The D2/D3 agonist quinpirole, which induces receptor internalization in vitro, was administered at graded d...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Sander, Christin Y, Hooker, Jacob M, Catana, Ciprian, Rosen, Bruce R, Mandeville, Joseph B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793127/
https://ncbi.nlm.nih.gov/pubmed/26388148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.296
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