Dimer formation by an N-terminal coiled coil in the APC protein.
Mutations in the human APC gene are associated with an inherited predisposition to colon cancer. APC codes for polypeptides of approximately 2800 amino acids, with sequence homologies to coiled-coil proteins in the first 900 residues. To determine the oligomerization properties of the APC protein, w...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11109 |
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