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Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
Tyrosine (Y)-recombinases have evolved to deliver mechanistically different reactions on a variety of substrates, but these evolutionary transitions are poorly understood. Among them, integron integrases are hybrid systems recombining single- and double-stranded DNA partners. These reactions are asy...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792948/ https://ncbi.nlm.nih.gov/pubmed/26961432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10937 |
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