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Synaptic Deficits at Neuromuscular Junctions in Two Mouse Models of Charcot–Marie–Tooth Type 2d

Patients with Charcot–Marie–Tooth Type 2D (CMT2D), caused by dominant mutations in Glycl tRNA synthetase (GARS), present with progressive weakness, consistently in the hands, but often in the feet also. Electromyography shows denervation, and patients often report that early symptoms include cramps...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Spaulding, Emily L., Sleigh, James N., Morelli, Kathryn H., Pinter, Martin J., Burgess, Robert W., Seburn, Kevin L.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792937/
https://ncbi.nlm.nih.gov/pubmed/26985035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1762-15.2016
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