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Synaptic Deficits at Neuromuscular Junctions in Two Mouse Models of Charcot–Marie–Tooth Type 2d

Patients with Charcot–Marie–Tooth Type 2D (CMT2D), caused by dominant mutations in Glycl tRNA synthetase (GARS), present with progressive weakness, consistently in the hands, but often in the feet also. Electromyography shows denervation, and patients often report that early symptoms include cramps...

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書目詳細資料
發表在:J Neurosci
Main Authors: Spaulding, Emily L., Sleigh, James N., Morelli, Kathryn H., Pinter, Martin J., Burgess, Robert W., Seburn, Kevin L.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792937/
https://ncbi.nlm.nih.gov/pubmed/26985035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1762-15.2016
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