Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stage II/III colon cancer

The Hippo pathway regulates tissue growth and cell fate. In colon cancer, Hippo pathway deregulation promotes cellular quiescence and resistance to 5-Fluorouracil. In this study 14 polymorphisms in 8 genes involved in the Hippo pathway (MST1, MST2, LATS1, LATS2, YAP, TAZ, FAT4 and RASSF1A) were eval...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Sebio, Ana, Matsusaka, Satoshi, Zhang, Wu, Yang, Dongyun, Ning, Yan, Stremitzer, Stefan, Stintzing, Sebastian, Sunakawa, Yu, Yamauchi, Shinichi, Fujimoto, Yoshiya, Ueno, Masashi, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792794/
https://ncbi.nlm.nih.gov/pubmed/26370619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.64
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