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Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction

BACKGROUND: Adult mammalian cardiomyocytes (CM) have the potential to proliferate, but this is not sufficient to generate adequate CMs after myocardial infarction (MI). The transcription factor Tbx20 is required for CM proliferation during development and adult CM homeostasis. The ability of Tbx20 o...

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Vydáno v:Circulation
Hlavní autoři: Xiang, Fu-li, Guo, Minzhe, Yutzey, Katherine E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792775/
https://ncbi.nlm.nih.gov/pubmed/26841808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.019357
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