A PPARγ agonist enhances bacterial clearance through neutrophil extracellular trap formation and improves survival in sepsis

Dysregulation of the inflammatory response against infection contributes to mortality in sepsis. Inflammation provides critical host defense, but it can cause tissue damage, multiple organ failure and death. Because the nuclear transcription factor peroxisome proliferator-activated receptor γ (PPARγ...

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Gepubliceerd in:Shock
Hoofdauteurs: Araújo, Cláudia V., Campbell, Clarissa, Gonçalves-de-Albuquerque, Cassiano F., Molinaro, Raphael, Cody, Mark J., Yost, Christian C., Bozza, Patricia T., Zimmerman, Guy A., Weyrich, Andrew S., Castro-Faria-Neto, Hugo C., Silva, Adriana R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792770/
https://ncbi.nlm.nih.gov/pubmed/26618986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000520
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