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Investigation of the therapeutic potential of N-acetyl cysteine and the tools used to define nigrostriatal degeneration in vivo

The glutathione precursor N-acetyl-L-cysteine (NAC) is currently being tested on Parkinson's patients for its neuroprotective properties. Our studies have shown that NAC can elicit protection in glutathione-independent manners in vitro. Thus, the goal of the present study was to establish an an...

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Bibliografiske detaljer
Udgivet i:Toxicol Appl Pharmacol
Main Authors: Nouraei, Negin, Zarger, Lauren, Weilnau, Justin N., Han, Jimin, Mason, Daniel M., Leak, Rehana K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792766/
https://ncbi.nlm.nih.gov/pubmed/26879220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.02.010
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