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Delivery of enteric neural progenitors with 5-HT(4) agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo

Cell therapy offers an innovative approach for treating enteric neuropathies. Postnatal gut-derived enteric neural stem/progenitor cells (ENSCs) represent a potential autologous source, but have a limited capacity for proliferation and neuronal differentiation. Since serotonin (5-HT) promotes enteri...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Hotta, Ryo, Cheng, Lily, Graham, Hannah K., Nagy, Nandor, Belkind-Gerson, Jaime, Mattheolabakis, George, Amiji, Mansoor M., Goldstein, Allan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792702/
https://ncbi.nlm.nih.gov/pubmed/26922325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.02.016
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