PPARα induces cell apoptosis by destructing Bcl2

PPARα belongs to the peroxisome-proliferator-activated receptors (PPARs) family, which plays a critical role in inhibiting cell proliferation and tumorigenesis, while the molecular mechanism is still unclear. Here we report that PPARα serves as an E3 ubiquitin ligase to govern Bcl2 protein stability...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gao, Jiaming, Liu, Qian, Xu, Ying, Gong, Xin, Zhang, Runyun, Zhou, Chenglin, Su, Zhaoliang, Jin, Jianhua, Shi, Haifeng, Shi, Juanjuan, Hou, Yongzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792581/
https://ncbi.nlm.nih.gov/pubmed/26556865
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