PPARα induces cell apoptosis by destructing Bcl2

PPARα belongs to the peroxisome-proliferator-activated receptors (PPARs) family, which plays a critical role in inhibiting cell proliferation and tumorigenesis, while the molecular mechanism is still unclear. Here we report that PPARα serves as an E3 ubiquitin ligase to govern Bcl2 protein stability...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Gao, Jiaming, Liu, Qian, Xu, Ying, Gong, Xin, Zhang, Runyun, Zhou, Chenglin, Su, Zhaoliang, Jin, Jianhua, Shi, Haifeng, Shi, Juanjuan, Hou, Yongzhong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792581/
https://ncbi.nlm.nih.gov/pubmed/26556865
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