Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition

Despite the common usage of radiotherapy for the treatment of NSCLC, outcomes for these cancers when treated with ionizing radiation (IR) are still unsatisfactory. A better understanding of the mechanisms underlying resistance to IR is needed to design approaches to eliminate the radioresistant cell...

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Udgivet i:Oncotarget
Main Authors: Gomez-Casal, Roberto, Epperly, Michael W., Wang, Hong, Proia, David A., Greenberger, Joel S., Levina, Vera
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792558/
https://ncbi.nlm.nih.gov/pubmed/26517240
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