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Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae

Cell senescence is dependent on the arrest in cell cycle. Here we studied the role of mitochondrial retrograde response signaling in yeast cell survival under a prolonged arrest. We have found that, unlike G1, long-term arrest in mitosis or S phase results in a loss of colony-forming abilities. Cons...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zyrina, Anna N., Sorokin, Maksim I., Sokolov, Sviatoslav S., Knorre, Dmitry A., Severin, Fedor F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792543/
https://ncbi.nlm.nih.gov/pubmed/26624981
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