Montelukast reduces seizures in pentylenetetrazol-kindled mice

Cysteinyl leukotrienes (CysLTs) have been implicated in seizures and kindling; however, the effect of CysLT receptor antagonists on seizure frequency in kindled animals and changes in CysLT receptor expression after pentylenetetrazol (PTZ)-induced kindling have not been investigated. In this study,...

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Détails bibliographiques
Publié dans:Braz J Med Biol Res
Auteurs principaux: Fleck, J., Temp, F.R., Marafiga, J.R., Jesse, A.C., Milanesi, L.H., Rambo, L.M., Mello, C.F.
Format: Artigo
Langue:Inglês
Publié: Associação Brasileira de Divulgação Científica 2016
Sujets:
Biomedical Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792507/
https://ncbi.nlm.nih.gov/pubmed/26909785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20155031
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