Fibronectin Modulates Cell Adhesion and Signaling to Promote Single Cell Migration of Highly Invasive Oral Squamous Cell Carcinoma

Cell migration is regulated by adhesion to the extracellular matrix (ECM) through integrins and activation of small RhoGTPases, such as RhoA and Rac1, resulting in changes to actomyosin organization. During invasion, epithelial-derived tumor cells switch from laminin-enriched basal membrane to colla...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ramos, Grasieli de Oliveira, Bernardi, Lisiane, Lauxen, Isabel, Sant’Ana Filho, Manoel, Horwitz, Alan Rick, Lamers, Marcelo Lazzaron
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792484/
https://ncbi.nlm.nih.gov/pubmed/26978651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151338
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