Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition

In fetal growth restriction (FGR), fetal growth is limited by reduced nutrient and oxygen supply. Insulin-like growth factor I (IGF-I) is a key regulator of fetal growth and IGF binding protein -1(IGFBP-1) is the principal regulator of fetal IGF-I bioavailability. Phosphorylation enhances IGFBP-1�...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Damerill, Ian, Biggar, Kyle K., Abu Shehab, Majida, Li, Shawn Shun-Cheng, Jansson, Thomas, Gupta, Madhulika B.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792228/
https://ncbi.nlm.nih.gov/pubmed/26714229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1194
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