Advantages of pure platelet-rich plasma compared with leukocyte- and platelet-rich plasma in promoting repair of bone defects

BACKGROUND: High levels of pro-inflammatory cytokines in leukocyte- and platelet-rich plasma (L-PRP) may activate the nuclear factor κB (NF-κB) pathway to counter the beneficial effect of the growth factors on bone regeneration. However, to date, no relevant studies have substantiated this. METHODS:...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Yin, Wenjing, Qi, Xin, Zhang, Yuelei, Sheng, Jiagen, Xu, Zhengliang, Tao, Shicong, Xie, Xuetao, Li, Xiaolin, Zhang, Changqing
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792107/
https://ncbi.nlm.nih.gov/pubmed/26980293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0825-9
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