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The position of lysosomes within the cell determines their luminal pH
We examined the luminal pH of individual lysosomes using quantitative ratiometric fluorescence microscopy and report an unappreciated heterogeneity: peripheral lysosomes are less acidic than juxtanuclear ones despite their comparable buffering capacity. An increased passive (leak) permeability to pr...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792074/ https://ncbi.nlm.nih.gov/pubmed/26975849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507112 |
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