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Novel impact of EWI-2, CD9, and CD81 on TGF-β signaling in melanoma
Cell surface transmembrane protein IGFS8 (herein called EWI-2) negatively regulates melanoma TGF-β signaling and is well positioned to control the transition in TGF-β signaling from cytostatic (in early melanoma stages) to pro-invasion/metastasis (in later stages). EWI-2 functions by sequestering th...
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發表在: | Mol Cell Oncol |
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Main Authors: | , |
格式: | Artigo |
語言: | Inglês |
出版: |
Taylor & Francis
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792032/ https://ncbi.nlm.nih.gov/pubmed/26989766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1030536 |
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