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Novel impact of EWI-2, CD9, and CD81 on TGF-β signaling in melanoma

Cell surface transmembrane protein IGFS8 (herein called EWI-2) negatively regulates melanoma TGF-β signaling and is well positioned to control the transition in TGF-β signaling from cytostatic (in early melanoma stages) to pro-invasion/metastasis (in later stages). EWI-2 functions by sequestering th...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Wang, Hong-Xing, Hemler, Martin E
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792032/
https://ncbi.nlm.nih.gov/pubmed/26989766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1030536
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