Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

BACKGROUND: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins in various signaling pathways, miR-21 is an attractive target for genetic and...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Peralta-Zaragoza, Oscar, Deas, Jessica, Meneses-Acosta, Angélica, De la O-Gómez, Faustino, Fernández-Tilapa, Gloria, Gómez-Cerón, Claudia, Benítez-Boijseauneau, Odelia, Burguete-García, Ana, Torres-Poveda, Kirvis, Bermúdez-Morales, Victor Hugo, Madrid-Marina, Vicente, Rodríguez-Dorantes, Mauricio, Hidalgo-Miranda, Alfredo, Pérez-Plasencia, Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791868/
https://ncbi.nlm.nih.gov/pubmed/26975392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2231-3
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