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Suppression of Sleep Spindle Rhythmogenesis in Mice with Deletion of Ca(V)3.2 and Ca(V)3.3 T-type Ca(2+) Channels

STUDY OBJECTIVES: Low-threshold voltage-gated T-type Ca(2+) channels (T-channels or CaV3 channels) sustain oscillatory discharges of thalamocortical (TC) and nucleus Reticularis thalami (nRt) cells. The CaV3.3 subtype dominates nRt rhythmic bursting and mediates a substantial fraction of spindle pow...

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Pubblicato in:Sleep
Autori principali: Pellegrini, Chiara, Lecci, Sandro, Lüthi, Anita, Astori, Simone
Natura: Artigo
Lingua:Inglês
Pubblicazione: Associated Professional Sleep Societies, LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791621/
https://ncbi.nlm.nih.gov/pubmed/26612388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5646
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