Apolipoprotein E ε4 Allele Genotype and the Effect of Depressive Symptoms on the Risk of Dementia in Men: The Honolulu-Asia Aging Study

CONTEXT: The apolipoprotein E ε4 (APOE ε4) allele is a genetic risk factor for Alzheimer disease. Recently, depression has also become recognized as a risk factor for dementia. However, the possible effect of the APOE genotype on the association between depression and dementia is unexamined. OBJECTI...

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Pubblicato in:Arch Gen Psychiatry
Autori principali: Irie, Fumiko, Masaki, Kamal H., Petrovitch, Helen, Abbott, Robert D., Ross, G. Webster, Taaffe, Dennis R., Launer, Lenore J., White, Lon R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791584/
https://ncbi.nlm.nih.gov/pubmed/18678795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archpsyc.65.8.906
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