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Impact of 4-epi-oxytetracycline on the gut microbiota and blood metabolomics of Wistar rats

The impact of 4-epi-oxytetracycline (4-EOTC), one of the main oxytetracycline (OTC) metabolites, on the gut microbiota and physiological metabolism of Wistar rats was analyzed to explore the dynamic alterations apparent after repeated oral exposure (0.5, 5.0 or 50.0 mg/kg bw) for 15 days as shown by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Han, Hongxing, Xiao, Hailong, Zhang, Kai, Lu, Zhenmei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791543/
https://ncbi.nlm.nih.gov/pubmed/26976662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23141
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