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Impact of New Genomic Technologies on Understanding Adverse Drug Reactions

It is well established that variations in genes can alter the pharmacokinetic and pharmacodynamic profile of a drug and immunological responses to it. Early advances in pharmacogenetics were made with traditional genetic techniques such as functional cloning of genes using knowledge gained from puri...

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Détails bibliographiques
Publié dans:Clin Pharmacokinet
Auteurs principaux: Maggo, Simran D. S., Savage, Ruth L., Kennedy, Martin A.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791456/
https://ncbi.nlm.nih.gov/pubmed/26369774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0324-9
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