Identification of small molecules that inhibit the histone chaperone Asf1 and its chromatin function

The eukaryotic genome is packed into chromatin, which is important for the genomic integrity and gene regulation. Chromatin structures are maintained through assembly and disassembly of nucleosomes catalyzed by histone chaperones. Asf1 (anti-silencing function 1) is a highly conserved histone chaper...

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Publicat a:BMB Rep
Autors principals: Seol, Ja-Hwan, Song, Tae-Yang, Oh, Se Eun, Jo, Chanhee, Choi, Ahreum, Kim, Byungho, Park, Jinyoung, Hong, Suji, Song, Ilrang, Jung, Kwan Young, Yang, Jae-Hyun, Park, Hwangseo, Ahn, Jin-Hyun, Han, Jeung-Whan, Cho, Eun-Jung
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Biochemistry and Molecular Biology 2015
Matèries:
Research-Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791324/
https://ncbi.nlm.nih.gov/pubmed/26058396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.12.063
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