Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model

Chromatin acetylation is attributed with distinct functional relevance with respect to gene expression in normal and diseased conditions thereby leading to a topical interest in the concept of epigenetic modulators and therapy. We report here the identification and characterization of the acetylatio...

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Publicado en:Oncotarget
Autores principales: Selvi, Ruthrotha B., Swaminathan, Amrutha, Chatterjee, Snehajyoti, Shanmugam, Muthu K., Li, Feng, Ramakrishnan, Gowsica B., Siveen, Kodappully Sivaraman, Chinnathambi, Arunachalam, Zayed, M. Emam, Alharbi, Sulaiman Ali, Basha, Jeelan, Bhat, Akshay, Vasudevan, Madavan, Dharmarajan, Arunasalam, Sethi, Gautam, Kundu, Tapas K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791268/
https://ncbi.nlm.nih.gov/pubmed/26517526
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