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Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies

Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs) is sufficient to capture most of the haplotype structure of the human genome. In this paper, we deve...

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Détails bibliographiques
Auteurs principaux: Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC479119/
https://ncbi.nlm.nih.gov/pubmed/15078859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1837404
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