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Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies

Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs) is sufficient to capture most of the haplotype structure of the human genome. In this paper, we deve...

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Detalhes bibliográficos
Main Authors: Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479119/
https://ncbi.nlm.nih.gov/pubmed/15078859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1837404
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