In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

The reinforcing and rewarding properties of cocaine are attributed to its ability to increase dopaminergic transmission in nucleus accumbens (NAc). This action reinforces drug taking and seeking and leads to potent and long-lasting associations between the rewarding effects of the drug and the cues...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Calipari, Erin S., Bagot, Rosemary C., Purushothaman, Immanuel, Davidson, Thomas J., Yorgason, Jordan T., Peña, Catherine J., Walker, Deena M., Pirpinias, Stephen T., Guise, Kevin G., Ramakrishnan, Charu, Deisseroth, Karl, Nestler, Eric J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791010/
https://ncbi.nlm.nih.gov/pubmed/26831103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521238113
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