Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

Factor H binding protein (fHbp) is a lipoprotein of Neisseria meningitidis important for the survival of the bacterium in human blood and a component of two recently licensed vaccines against serogroup B meningococcus (MenB). Based on 866 different amino acid sequences this protein is divided into t...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Biagini, Massimiliano, Spinsanti, Marco, De Angelis, Gabriella, Tomei, Sara, Ferlenghi, Ilaria, Scarselli, Maria, Rigat, Fabio, Messuti, Nicola, Biolchi, Alessia, Muzzi, Alessandro, Anderloni, Giulia, Brunelli, Brunella, Cartocci, Elena, Buricchi, Francesca, Tani, Chiara, Stella, Maria, Moschioni, Monica, Del Tordello, Elena, Colaprico, Annalisa, Savino, Silvana, Giuliani, Marzia M., Delany, Isabel, Pizza, Mariagrazia, Costantino, Paolo, Norais, Nathalie, Rappuoli, Rino, Masignani, Vega
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791009/
https://ncbi.nlm.nih.gov/pubmed/26888286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521142113
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