Vβ14(+) T Cells Mediate the Vaccine-Enhanced Disease Induced by Immunization with Respiratory Syncytial Virus (RSV) G Glycoprotein but Not with Formalin-Inactivated RSV

Mice immunized with respiratory syncytial virus (RSV) G glycoprotein or with formalin-inactivated RSV (FI-RSV) exhibit severe disease following RSV challenge. This results in type 2 cytokine production and pulmonary eosinophilia, both hallmarks of vaccine-enhanced disease. RSV G-induced T-cell respo...

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Bibliographic Details
Main Authors: Johnson, Teresa R., Varga, Steven M., Braciale, Thomas J., Graham, Barney S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC479099/
https://ncbi.nlm.nih.gov/pubmed/15280483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8753-8760.2004
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