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Junctophilin-4, a component of the endoplasmic reticulum–plasma membrane junctions, regulates Ca(2+) dynamics in T cells
Orai1 and stromal interaction molecule 1 (STIM1) mediate store-operated Ca(2+) entry (SOCE) in immune cells. STIM1, an endoplasmic reticulum (ER) Ca(2+) sensor, detects store depletion and interacts with plasma membrane (PM)-resident Orai1 channels at the ER–PM junctions. However, the molecular comp...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4790987/ https://ncbi.nlm.nih.gov/pubmed/26929330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524229113 |
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