In Vitro and In Vivo Investigation of the Angiogenic Effects of Liraglutide during Islet Transplantation

INTRODUCTION: This study investigated the angiogenic properties of liraglutide in vitro and in vivo and the mechanisms involved, with a focus on Hypoxia Inducible Factor-1α (HIF-1α) and mammalian target of rapamycin (mTOR). MATERIALS AND METHODS: Rat pancreatic islets were incubated in vitro with 10...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Langlois, Allan, Mura, Carole, Bietiger, William, Seyfritz, Elodie, Dollinger, Camille, Peronet, Claude, Maillard, Elisa, Pinget, Michel, Jeandidier, Nathalie, Sigrist, Séverine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790919/
https://ncbi.nlm.nih.gov/pubmed/26974949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147068
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