Herpes Simplex Virus 1 Induces Cytoplasmic Accumulation of TIA-1/TIAR and both Synthesis and Cytoplasmic Accumulation of Tristetraprolin, Two Cellular Proteins That Bind and Destabilize AU-Rich RNAs

Herpes simplex virus 1 causes a shutoff of cellular protein synthesis through the degradation of RNA that is mediated by the virion host shutoff (Vhs) protein encoded by the U(L)41 gene. We reported elsewhere that the Vhs-dependent degradation of RNA is selective, and we identified RNAs containing A...

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Bibliographic Details
Main Authors: Esclatine, Audrey, Taddeo, Brunella, Roizman, Bernard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC479066/
https://ncbi.nlm.nih.gov/pubmed/15280467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8582-8592.2004
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