Role of Alix in miRNA packaging during extracellular vesicle biogenesis

Evidence indicates that Alix, an accessory protein of the endosomal sorting complex required for transport (ESCRT), is involved in the biogenesis of extracellular vesicles (EVs). EVs contain selected patterns of microRNAs (miRNAs or miRs); however, little is known about the mechanisms of miRNA enric...

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Bibliographic Details
Published in:Int J Mol Med
Main Authors: IAVELLO, ALESSANDRA, FRECH, VALESKA S.L., GAI, CHIARA, DEREGIBUS, MARIA CHIARA, QUESENBERRY, PETER J., CAMUSSI, GIOVANNI
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790646/
https://ncbi.nlm.nih.gov/pubmed/26935291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2488
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