Putative Autocleavage of Outer Capsid Protein μ1, Allowing Release of Myristoylated Peptide μ1N during Particle Uncoating, Is Critical for Cell Entry by Reovirus

Several nonenveloped animal viruses possess an autolytic capsid protein that is cleaved as a maturation step during assembly to yield infectious virions. The 76-kDa major outer capsid protein μ1 of mammalian orthoreoviruses (reoviruses) is also thought to be autocatalytically cleaved, yielding the v...

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Detalles Bibliográficos
Main Authors: Odegard, Amy L., Chandran, Kartik, Zhang, Xing, Parker, John S. L., Baker, Timothy S., Nibert, Max L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Structure and Assembly
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC479062/
https://ncbi.nlm.nih.gov/pubmed/15280481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8732-8745.2004
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