Caspases Mediate Processing of the Capsid Precursor and Cell Release of Human Astroviruses

In this work we have shown that astrovirus infection induces apoptosis of Caco-2 cells, since fragmentation of cellular DNA, cleavage of cellular proteins which are substrate of activated caspases, and a change in the mitochondrial transmembrane potential occur upon virus infection. The human astrov...

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Bibliographic Details
Main Authors: Méndez, Ernesto, Salas-Ocampo, Elizabeth, Arias, Carlos F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC479052/
https://ncbi.nlm.nih.gov/pubmed/15280469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8601-8608.2004
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