Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study

Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown. In a previous pilot study, L-T4 treatment reduced depression scores and activity within the anterior limbic network. Here...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Bauer, M, Berman, S, Stamm, T, Plotkin, M, Adli, M, Pilhatsch, M, London, E D, Hellemann, G S, Whybrow, P C, Schlagenhauf, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790155/
https://ncbi.nlm.nih.gov/pubmed/25600111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.186
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